The following table shows the number of participants and the tools available in each wave:
Participants
| C11 Baseline 2011-2012 | C11 2nd. wave 2014-2015 | C11 3rd. wave 2018 | C19 Baseline 2019-2021 | C19 Substudy COVID 2020 | C11 4th. wave 2022 | C19 2nd. wave 2023 | C11 5th. wave 2025 | C19 3rd. wave 2025 | |
| Cohort 2011 (C11) | 4.753 | 2.528 | 1.577 | – | – | 963 | – | – | – |
| Cohort 2019 (C19) | – | – | – | 3.002 | 1.166 | – | 1.441 | – | – |
Tools
| Tools | C11 Baseline 2011-2012 | C11 2nd. wave 2014-2015 | C11 3rd. wave 2018 | C19 Baseline 2019-2021 | C19 Substudy COVID 2020 | C11 4th. wave 2022 | C19 2nd. wave 2023 | C11 5th. wave 2025 | C19 3rd. wave 2025 |
| Household composition | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Sociodemographic features | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Cognitive reserve questionnaire (Rami et al., 2011) | X | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Mini Mental State Examination (Lobo et al., 1979) | X | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Work history and benefits | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| The employment precariousness scale (Padrosa, 2021) | X | X | X | X | X | X | ✔ | X | X |
| Disability assessment (WHO-DAS II), 12 items (Luciano et al., 2010) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Basic and instrumental activities of daily living | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Multidimensional assessment of health condition (Salomon et al., 2003) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Blood pressure | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Weight and height | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Waist circumference | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Walking speed | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Vision (near and distance) | ✔ | ✔ | ✔ | X | X | X | X | X | X |
| Grip strength | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Immediate and delayed recall. Consortium to establish an Alzheimer’s disease registry (Morris et al., 1989) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Forward and backward digit span tests of the Wechsler Adult Intelligence Scale (2008) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Verbal fluency. Animal naming technique (Rosen et al., 1980) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Trail Making Test (Bowie & Harvey, 2006) | X | X | X | X | X | ✔ | X | X | X |
| Tobacco and alcohol consumption | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ |
| Mediterranean Diet Adherence Screener (MEDAS) (Martínez-González et al., 2012) | X | ✔ | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ |
| Short screening questionnaire of highly processed food consumption (sQ-HPF) (Martínez-Pérez et al., 2022) | X | X | X | X | X | X | ✔ | X | ✔ |
| Mini-nutritional assessment (Kaiser et al., 2009) | X | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Global Physical Activity Questionnaire (GPAQ) version 2 (Armstrong and Bull, 2006) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ |
| Chronic conditions (e.g. diabetes, stroke, asthma, hypertension, etc.), | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Angina (Rose, 1962) | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Injuries | ✔ | X | X | X | X | X | X | X | X |
| Urinary incontinence (Espuña et al., 2004) | X | X | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Depression (Kessler & Üstun, 2004) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Generalized anxiety (Kessler & Üstun, 2004) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Panic disorder or attack (Kessler & Üstun, 2004) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Suicide (Kessler & Üstun, 2004) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Agoraphobia (Kessler & Üstun, 2004) | X | X | X | ✔ | X | X | ✔ | X | ✔ |
| The List of Threatening Experiences (Brugha & Cragg, 1990) | X | X | X | ✔ | X | X | X | X | X |
| Health care utilization and health system coverage | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Eysenck personality questionnaire, N, E and S scales (Sandín et al., 2002) | X | X | X | ✔ | X | X | X | X | X |
| Social networks (Zawisza et al., 2014), social trust and safety | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Social participation. Based on the social isolation scale (Shankar et al., 2011) | X | X | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| OSLO Social Support Scale (OSS-3) (Kocalevent et al., 2018) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| UCLA Loneliness Scale, 3 items (Hughes et al., 2004) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| The multidimensional scale of perceived social support (Zimet, 1990) | X | X | X | X | X | X | ✔ | X | ✔ |
| Suspicion of abuse of the elderly (Pérez-Rojo et al., 2008) | X | X | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Caregiver’s burden (Zarit, 1980) | X | X | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Households in material deprivation (INE, 2021) | X | X | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Subjective Socioeconomic Status (Präg et al., 2016) | X | X | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Quality of life (WHOQOL-AGE) (Caballero et al., 2013) | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Perceived well-being scale (Cantril, 1965) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Stress | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Reconstruction of daily life (Kahneman, 2004) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Sleep quality (Royuela & Macías, 1997) | X | X | X | ✔ | ✔ | X | ✔ | X | ✔ |
| Subjective well-being (Diener et al., 2009) | X | X | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Brief resilience scale (Rodríguez-Rey et al., 2016) | X | X | X | ✔ | ✔ | X | ✔ | X | ✔ |
| Built Environment Self-Reported Questionnaire (Raggi et al., 2014) | ✔ | X | X | X | X | X | X | X | X |
| Time in green spaces and built environment | X | X | X | X | X | X | ✔ | X | ✔ |
| Economic and social impact of the COVID-19 pandemic | X | X | X | X | X | ✔ | ✔ | X | X |
| Short 15-item Big Five Inventory (BFI-S) (Lang et al., 2011) | X | X | X | X | X | X | X | X | ✔ |
| 6-Item De Jong Gierveld Loneliness Scale (Gierveld et al., 2006) | X | X | X | X | X | X | X | X | ✔ |
| 12-item Expectations Regarding Aging Survey (Sarkisian et al., 2005) | X | X | X | X | X | X | X | X | ✔ |
| DNA test | X | X | X | X | X | X | ✔ | ✔ | X |
| Mortality | X | ✔ | ✔ | X | X | ✔ | ✔ | ✔ | ✔ |
| Interviewer evaluation | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| COVID sub-study questionnaire | |||||||||
| Questions about COVID infection | X | X | X | X | ✔ | X | X | X | X |
| Social relationships during confinement | X | X | X | X | ✔ | X | X | X | X |
| Pain | X | X | X | X | ✔ | X | X | X | X |
| Self-reported weight | X | X | X | X | ✔ | X | X | X | X |
| Screen use | X | X | X | X | ✔ | X | X | X | X |
| Economic aspects and unemployment | X | X | X | X | ✔ | X | X | X | X |
| Proxy questionnaire | |||||||||
| Informant Questionnaire on Cognitive Impairment in the Elderly (IQCODE-Short Form) (Jorm et al., 1994) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
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