The following table shows the number of participants and the tools available in each wave:
Participants
| C11 Baseline 2011-2012 | C11 2nd. wave 2014-2015 | C11 3rd. wave 2018 | C19 Baseline 2019-2021 | C19 Substudy COVID 2020 | C11 4th. wave 2022 | C19 2nd. wave 2023-2024 | C11 5th. wave 2025 | C19 3rd. wave 2025 | |
| Cohort 2011 (C11) | 4.753 | 2.526 | 1.577 | – | – | 963 | – | 595 | – |
| Cohort 2019 (C19) | – | – | – | 3.002 | 1.166 | – | 1.441 | – | 835 |
Tools
| Tools | C11 Baseline 2011-2012 | C11 2nd. wave 2014-2015 | C11 3rd. wave 2018 | C19 Baseline 2019-2021 | C19 Substudy COVID 2020 | C11 4th. wave 2022 | C19 2nd. wave 2023- 2024 | C11 5th. wave 2025 | C19 3rd. wave 2025 |
| Household composition | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Sociodemographic features | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Cognitive reserve questionnaire (Rami et al., 2011) | X | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Mini Mental State Examination (Lobo et al., 1979) | X | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Work history and benefits | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| The employment precariousness scale (Padrosa, 2021) | X | X | X | X | X | X | ✔ | X | X |
| Disability assessment (WHO-DAS II), 12 items (Luciano et al., 2010) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Basic and instrumental activities of daily living | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Multidimensional assessment of health condition (Salomon et al., 2003) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Blood pressure | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Weight and height | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Waist circumference | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Walking speed | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Vision (near and distance) | ✔ | ✔ | ✔ | X | X | X | X | X | X |
| Grip strength | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Immediate and delayed recall. Consortium to establish an Alzheimer’s disease registry (Morris et al., 1989) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Forward and backward digit span tests of the Wechsler Adult Intelligence Scale (2008) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Verbal fluency. Animal naming technique (Rosen et al., 1980) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Trail Making Test (Bowie & Harvey, 2006) | X | X | X | X | X | ✔ | X | X | X |
| Tobacco and alcohol consumption | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ |
| Mediterranean Diet Adherence Screener (MEDAS) (Martínez-González et al., 2012) | X | ✔ | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ |
| Short screening questionnaire of highly processed food consumption (sQ-HPF) (Martínez-Pérez et al., 2022) | X | X | X | X | X | X | ✔ | X | ✔ |
| Mini-nutritional assessment (Kaiser et al., 2009) | X | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Global Physical Activity Questionnaire (GPAQ) version 2 (Armstrong and Bull, 2006) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ |
| Chronic conditions (e.g. diabetes, stroke, asthma, hypertension, etc.), | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Angina (Rose, 1962) | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Injuries | ✔ | X | X | X | X | X | X | X | X |
| Urinary incontinence (Espuña et al., 2004) | X | X | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Depression (Kessler & Üstun, 2004) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Generalized anxiety (Kessler & Üstun, 2004) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Panic disorder or attack (Kessler & Üstun, 2004) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Suicide (Kessler & Üstun, 2004) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Agoraphobia (Kessler & Üstun, 2004) | X | X | X | ✔ | X | X | ✔ | X | ✔ |
| The List of Threatening Experiences (Brugha & Cragg, 1990) | X | X | X | ✔ | X | X | X | X | X |
| Health care utilization and health system coverage | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Eysenck personality questionnaire, N, E and S scales (Sandín et al., 2002) | X | X | X | ✔ | X | X | X | X | X |
| Social networks (Zawisza et al., 2014), social trust and safety | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Social participation. Based on the social isolation scale (Shankar et al., 2011) | X | X | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| OSLO Social Support Scale (OSS-3) (Kocalevent et al., 2018) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| UCLA Loneliness Scale, 3 items (Hughes et al., 2004) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| The multidimensional scale of perceived social support (Zimet, 1990) | X | X | X | X | X | X | ✔ | X | ✔ |
| Suspicion of abuse of the elderly (Pérez-Rojo et al., 2008) | X | X | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Caregiver’s burden (Zarit, 1980) | X | X | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Households in material deprivation (INE, 2021) | X | X | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Subjective Socioeconomic Status (Präg et al., 2016) | X | X | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Quality of life (WHOQOL-AGE) (Caballero et al., 2013) | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | ✔ |
| Perceived well-being scale (Cantril, 1965) | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
| Stress | ✔ | ✔ | ✔ | ✔ | X | ✔ | X | ✔ | X |
| Reconstruction of daily life (Kahneman, 2004) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Sleep quality (Royuela & Macías, 1997) | X | X | X | ✔ | ✔ | X | ✔ | X | ✔ |
| Subjective well-being (Diener et al., 2009) | X | X | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| Brief resilience scale (Rodríguez-Rey et al., 2016) | X | X | X | ✔ | ✔ | X | ✔ | X | ✔ |
| Built Environment Self-Reported Questionnaire (Raggi et al., 2014) | ✔ | X | X | X | X | X | X | X | X |
| Time in green spaces and built environment | X | X | X | X | X | X | ✔ | X | ✔ |
| Economic and social impact of the COVID-19 pandemic | X | X | X | X | X | ✔ | ✔ | X | X |
| Short 15-item Big Five Inventory (BFI-S) (Lang et al., 2011) | X | X | X | X | X | X | X | X | ✔ |
| 6-Item De Jong Gierveld Loneliness Scale (Gierveld et al., 2006) | X | X | X | X | X | X | X | X | ✔ |
| 12-item Expectations Regarding Aging Survey (Sarkisian et al., 2005) | X | X | X | X | X | X | X | X | ✔ |
| 10-item Adverse child scale (Felitti et al., 1998) | X | X | X | X | X | X | X | ✔ | ✔ |
| DNA test | X | X | X | X | X | X | ✔ | ✔ | X |
| Mortality | X | ✔ | ✔ | X | X | ✔ | ✔ | ✔ | ✔ |
| Interviewer evaluation | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
| COVID sub-study questionnaire | |||||||||
| Questions about COVID infection | X | X | X | X | ✔ | X | X | X | X |
| Social relationships during confinement | X | X | X | X | ✔ | X | X | X | X |
| Pain | X | X | X | X | ✔ | X | X | X | X |
| Self-reported weight | X | X | X | X | ✔ | X | X | X | X |
| Screen use | X | X | X | X | ✔ | X | X | X | X |
| Economic aspects and unemployment | X | X | X | X | ✔ | X | X | X | X |
| Proxy questionnaire | |||||||||
| Informant Questionnaire on Cognitive Impairment in the Elderly (IQCODE-Short Form) (Jorm et al., 1994) | ✔ | ✔ | ✔ | ✔ | X | ✔ | ✔ | ✔ | ✔ |
References
Armstrong, T., & Bull, F. (2006). Development of the world health organization global physical activity questionnaire (GPAQ). Journal of Public Health, 14(2), 66-70.
Bowie, C. R., & Harvey, P. D. (2006). Administration and interpretation of the Trail Making Test. Nature protocols, 1(5), 2277-2281.
Brugha, T. S., & Cragg, D. (1990). The list of threatening experiences: the reliability and validity of a brief life events questionnaire. Acta Psychiatrica Scandinavica, 82(1), 77-81.
Caballero, F. F., Miret, M., Power, M., Chatterji, S., Tobiasz-Adamczyk, B., Koskinen, S., … & Ayuso-Mateos, J. L. (2013). Validation of an instrument to evaluate quality of life in the aging population: WHOQOL-AGE. Health and quality of life outcomes, 11(1), 177.
Cantril, H. (1965). The pattern of human concern. New Brunswick: Rutgers University.
Diener, E., Wirtz, D., Tov, W., Kim-Prieto, C., Choi, D. W., Oishi, S., et al. (2010). New well-being measures: Short scales to assess flourishing and positive and negative feelings. Social Indicators Research, 97, 143–156.
Espuña Pons, M., Rebollo Álvarez, P., & Puig Clota, M. (2004). Validación de la versión española del International Consultation on Incontinence Questionnaire-Short Form. Un cuestionario para evaluar la incontinencia urinaria. Medicina clinica, 122(8), 288-292.
Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., & Marks, J. S. (1998). Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: The Adverse Childhood Experiences (ACE) Study. American journal of preventive medicine, 14(4), 245-258.
Gierveld, J. D. J., & Tilburg, T. V. (2006). A 6-item scale for overall, emotional, and social loneliness: Confirmatory tests on survey data. Research on aging, 28(5), 582-598.
Hughes, M. E., Waite, L. J., Hawkley, L. C., & Cacioppo, J. T. (2004). A short scale for measuring loneliness in large surveys: Results from two population-based studies. Research on aging, 26(6), 655-672.
Instituto Nacional de Estadística (INE, 2021). “Riesgo de pobreza y/o exclusión social.
Estrategia Europa 2020. Indicador AROPE”. Available at: https://www.ine.es/ss/Satellite?L=es_ES&c=INESeccion_C&cid=1259941637944&p=1254735110672&pagename=ProductosYServicios/PYSLayout
Jorm, A. F. (1994). A short form of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): development and cross-validation. Psychological medicine, 24(1), 145-153.
Kahneman, D., Krueger, A. B., Schkade, D. A., Schwarz, N., & Stone, A. A. (2004). A survey method for characterizing daily life experience: The day reconstruction method. Science, 306(5702), 1776-1780.
Kaiser, M. J., Bauer, J. M., Ramsch, C., Uter, W., Guigoz, Y., Cederholm, T., … & Tsai, A. C. (2009). Validation of the Mini Nutritional Assessment Short-Form (MNA®-SF): A practical tool for identification of nutritional status. JNHA-The Journal of Nutrition, Health and Aging, 13(9), 782.
Kessler, R. C., & Üstün, T. B. (2004). The world mental health (WMH) survey initiative version of the world health organization (WHO) composite international diagnostic interview (CIDI). International journal of methods in psychiatric research, 13(2), 93-121.
Kocalevent, R. D., Berg, L., Beutel, M. E., Hinz, A., Zenger, M., Härter, M., … & Brähler, E. (2018). Social support in the general population: standardization of the Oslo social support scale (OSSS-3). BMC psychology, 6(1), 31.
Lang, F. R., John, D., Lüdtke, O., Schupp, J., & Wagner, G. G. (2011). Short assessment of the Big Five: Robust across survey methods except telephone interviewing. Behavior research methods, 43, 548-567.
Lobo, A., Gómez, A., & Folstein, M. F. (1979). El” Mini-examen cognocitivo” en pacientes geriártricos. Folia neuropsiquiátrica: Revista de psicología, psiquiatría y ciencias afines, 14(1), 245-251.
Luciano, J. V., Ayuso-Mateos, J. L., Aguado, J., Fernandez, A., Serrano-Blanco, A., Roca, M., & Haro, J. M. (2010). The 12-item world health organization disability assessment schedule II (WHO-DAS II): a nonparametric item response analysis. BMC medical research methodology, 10(1), 45.
Martínez-González, M. A., García-Arellano, A., Toledo, E., Salas-Salvado, J., Buil-Cosiales, P., Corella, D., … & Fiol, M. (2012). A 14-item Mediterranean diet assessment tool and obesity indexes among high-risk subjects: the PREDIMED trial. PloS one, 7(8), e43134.
Martinez-Perez, C., Daimiel, L., Climent-Mainar, C., Martínez-González, M. Á., Salas-Salvadó, J., Corella, D., … & San-Cristobal, R. (2022). Integrative development of a short screening questionnaire of highly processed food consumption (sQ-HPF). International Journal of Behavioral Nutrition and Physical Activity, 19(1), 1-16.
Morris, J. C., Mohs, R. C., & Rogers, H. (1989). Consortium To Establish a Registry for Alzheimer’s Disease (CERAD) Clinical and Neuropsychological. Psychopharmacology bulletin, 24(3-4), 641.
Padrosa, E., Belvis, F., Benach, J., & Julià, M. (2021). Measuring precarious employment in the European Working Conditions Survey: psychometric properties and construct validity in Spain. Quality & quantity, 55(2), 543-562.
Pérez-Rojo, G., Castiello, M. T. S., & Jaquotot, M. T. A. (2008). Aportación española a los avances internacionales en la adaptación lingüística y cultural de un instrumento de detección de sospecha de maltrato hacia personas mayores. Revista Española de Geriatría y Gerontología, 43(3), 180-188.
Präg, P., Mills, M. C., & Wittek, R. (2016). Subjective socioeconomic status and health in cross-national comparison. Social Science & Medicine, 149, 84-92.
Raggi, A., Quintas, R., Bucciarelli, P., Franco, M. G., Andreotti, A., Miret, M., … & Leonardi, M. (2014). Validation of the COURAGE Built Environment Self‐Reported Questionnaire. Clinical Psychology & Psychotherapy, 21(3), 215-226.
Rami, L., Valls-Pedret, C., Bartrés-Faz, D., Caprile, C., Solé-Padullés, C., Castellví, M., … & Molinuevo, J. (2011). Cuestionario de reserva cognitiva. Valores obtenidos en población anciana sana y con enfermedad de Alzheimer. Revista de Neurología, 52(4), 195-201.
Rodríguez-Rey, R., Alonso-Tapia, J., & Hernansaiz-Garrido, H. (2016). Reliability and validity of the Brief Resilience Scale (BRS) Spanish Version. Psychological assessment, 28(5), e101.
Rosen, W. G. (1980). Verbal fluency in aging and dementia. Journal of clinical and experimental neuropsychology, 2(2), 135-146.
Royuela, A. & Macías, J.A. (1997). Propiedades clinimétricas de la versión castellana. Vigilia-sueño, 9(2), 81-94.
Salomon, J. A., Mathers, C. D., Chatterji, S., Sadana, R., Ustun, T. B., & Murray, C. J. (2003). Quantifying individual levels of health: definitions, concepts and measurement issues. Health Systems Performance Assessment: Debate, Methods, and Empiricism, 301-18.
Sandín, B., Valiente, R. M., Montes, M. O., Chorot, P., & Germán, M. A. S. (2002). Versión española del cuestionario EPQR-Abreviado (EPQR-A)(II): Replicación factorial, fiabilidad y validez. Revista de psicopatología y psicología clínica, 7(3), 207-216.
Sarkisian, C. A., Steers, W. N., Hays, R. D., & Mangione, C. M. (2005). Development of the 12-item expectations regarding aging survey. The Gerontologist, 45(2), 240-248.
Shankar, A., McMunn, A., Banks, J., & Steptoe, A. (2011). Loneliness, social isolation, and behavioral and biological health indicators in older adults. Health Psychology, 30(4), 377.
Wechsler, D. (2008). Wechsler adult intelligence scale–Fourth Edition (WAIS–IV). San Antonio, TX: NCS Pearson, 22(498), 1.
Zarit, S. H., Reever, K. E., & Bach-Peterson, J. (1980). Relatives of the impaired elderly: correlates of feelings of burden. The gerontologist, 20(6), 649-655.
Zawisza, K., Galas, A., Tobiasz‐Adamczyk, B., Chatterji, S., Haro, J. M., Miret, M., … & Leonardi, M. (2014). The validity of the instrument to evaluate social network in the ageing population: the Collaborative Research on Ageing in Europe Social Network Index. Clinical psychology & psychotherapy, 21(3), 227-241.
Zimet, G. D., Powell, S. S., Farley, G. K., Werkman, S., & Berkoff, K. A. (1990). Psychometric characteristics of the multidimensional scale of perceived social support. Journal of personality assessment, 55(3-4), 610-617.
